TY  - GEN
AU  - Tecle,H
AU  - Barrett,S D
AU  - Lauffer,D J
AU  - Augelli-Szafran,C
AU  - Brann,M R
AU  - Callahan,M J
AU  - Caprathe,B W
AU  - Davis,R E
AU  - Doyle,P D
AU  - Eubanks,D
AU  - Lipiniski,W
AU  - Mirzadegan,T
AU  - Moos,W H
AU  - Moreland,D W
AU  - Nelson,C B
AU  - Pavia,M R
AU  - Raby,C
AU  - Schwarz,R D
AU  - Spencer,C J
AU  - Thomas,A J
AU  - Jaen,J C
TI  - Design and synthesis of m1-selective muscarinic agonists: (R)-(-)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3'-methoxyphenyl)-2-propynyl)oxime maleate (CI-1017), a functionally m1-selective muscarinic agonist
SN  - 0022-2623
PY  - 1998///0724
KW  - 3T3 Cells
KW  - Adenylyl Cyclase Inhibitors
KW  - Animals
KW  - Bridged Bicyclo Compounds, Heterocyclic
KW  - chemical synthesis
KW  - CHO Cells
KW  - Cricetinae
KW  - Drug Design
KW  - Enzyme Inhibitors
KW  - Humans
KW  - Inositol Phosphates
KW  - biosynthesis
KW  - Male
KW  - Memory
KW  - drug effects
KW  - Mice
KW  - Muscarinic Agonists
KW  - Oximes
KW  - Rats
KW  - Receptor, Muscarinic M1
KW  - Receptors, Muscarinic
KW  - Stereoisomerism
KW  - Structure-Activity Relationship
KW  - Transfection
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm960683m
ER  -