TY - GEN AU - Sinclair,J AU - Jeffery,E AU - Wrighton,S AU - Kostrubsky,V AU - Szakacs,J AU - Wood,S AU - Sinclair,P TI - Alcohol-mediated increases in acetaminophen hepatotoxicity: role of CYP2E and CYP3A SN - 0006-2952 PY - 1998///0702 KW - Acetaminophen KW - adverse effects KW - Animals KW - Aryl Hydrocarbon Hydroxylases KW - Biotransformation KW - Cytochrome P-450 CYP2E1 KW - metabolism KW - Cytochrome P-450 CYP2E1 Inhibitors KW - Cytochrome P-450 CYP3A KW - Cytochrome P-450 Enzyme Inhibitors KW - Cytochrome P-450 Enzyme System KW - Drug Synergism KW - Enzyme Inhibitors KW - pharmacology KW - Ethanol KW - Liver KW - drug effects KW - Oxidoreductases, N-Demethylating KW - antagonists & inhibitors KW - Substance Withdrawal Syndrome N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review UR - https://doi.org/10.1016/s0006-2952(97)00656-4 ER -