TY  - GEN
AU  - Bell,I M
AU  - Erb,J M
AU  - Freidinger,R M
AU  - Gallicchio,S N
AU  - Guare,J P
AU  - Guidotti,M T
AU  - Halpin,R A
AU  - Hobbs,D W
AU  - Homnick,C F
AU  - Kuo,M S
AU  - Lis,E V
AU  - Mathre,D J
AU  - Michelson,S R
AU  - Pawluczyk,J M
AU  - Pettibone,D J
AU  - Reiss,D R
AU  - Vickers,S
AU  - Williams,P D
AU  - Woyden,C J
TI  - Development of orally active oxytocin antagonists: studies on 1-(1-[4-[1-(2-methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2- methoxybenzoyl]piperidin-4-yl)-1,4-dihydrobenz[d][1,3]oxazin-2-one (L-372,662) and related pyridines
SN  - 0022-2623
PY  - 1998///0624
KW  - Administration, Oral
KW  - Animals
KW  - Biological Availability
KW  - Cell Line
KW  - Chromatography, High Pressure Liquid
KW  - Dogs
KW  - Female
KW  - Humans
KW  - Kidney
KW  - cytology
KW  - Liver
KW  - metabolism
KW  - Male
KW  - Mass Spectrometry
KW  - Oxazines
KW  - chemical synthesis
KW  - Pregnancy
KW  - Pyridines
KW  - Rats
KW  - Receptors, Oxytocin
KW  - antagonists & inhibitors
KW  - Recombinant Proteins
KW  - Spectrophotometry, Ultraviolet
KW  - Uterine Contraction
KW  - drug effects
KW  - Uterus
N1  - Publication Type: Comparative Study; Journal Article
UR  - https://doi.org/10.1021/jm9800797
ER  -