TY - GEN AU - von Janta-Lipinski,M AU - Costisella,B AU - Ochs,H AU - Hübscher,U AU - Hafkemeyer,P AU - Matthes,E TI - Newly synthesized L-enantiomers of 3'-fluoro-modified beta-2'-deoxyribonucleoside 5'-triphosphates inhibit hepatitis B DNA polymerases but not the five cellular DNA polymerases alpha, beta, gamma, delta, and epsilon nor HIV-1 reverse transcriptase SN - 0022-2623 PY - 1998///0624 KW - Animals KW - Cattle KW - DNA Polymerase I KW - antagonists & inhibitors KW - DNA Polymerase II KW - DNA Polymerase III KW - DNA Polymerase beta KW - DNA Polymerase gamma KW - DNA-Directed DNA Polymerase KW - isolation & purification KW - Enzyme Inhibitors KW - chemical synthesis KW - HIV Reverse Transcriptase KW - HeLa Cells KW - Hepatitis B KW - enzymology KW - Hepatitis B Virus, Duck KW - Humans KW - Kinetics KW - Nucleic Acid Synthesis Inhibitors KW - Organophosphates KW - Placenta KW - Pyrimidine Nucleosides KW - Reverse Transcriptase Inhibitors KW - Stereoisomerism KW - Structure-Activity Relationship N1 - Publication Type: Comparative Study; Journal Article UR - https://doi.org/10.1021/jm9704210 ER -