von Janta-Lipinski, M <br/><br/>
Newly synthesized L-enantiomers of 3'-fluoro-modified beta-2'-deoxyribonucleoside 5'-triphosphates inhibit hepatitis B DNA polymerases but not the five cellular DNA polymerases alpha, beta, gamma, delta, and epsilon nor HIV-1 reverse transcriptase.  [electronic resource] 

 -  Journal of medicinal chemistry  Jun 1998 
 - 2040-6 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm9704210  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Cattle<br/>DNA Polymerase I--antagonists & inhibitors<br/>DNA Polymerase II--antagonists & inhibitors<br/>DNA Polymerase III--antagonists & inhibitors<br/>DNA Polymerase beta--antagonists & inhibitors<br/>DNA Polymerase gamma<br/>DNA-Directed DNA Polymerase--isolation & purification<br/>Enzyme Inhibitors--chemical synthesis<br/>HIV Reverse Transcriptase--antagonists & inhibitors<br/>HeLa Cells<br/>Hepatitis B--enzymology<br/>Hepatitis B Virus, Duck--enzymology<br/>Humans<br/>Kinetics<br/>Nucleic Acid Synthesis Inhibitors<br/>Organophosphates--chemical synthesis<br/>Placenta--enzymology<br/>Pyrimidine Nucleosides--chemical synthesis<br/>Reverse Transcriptase Inhibitors--chemical synthesis<br/>Stereoisomerism<br/>Structure-Activity Relationship