TY  - GEN
AU  - Egorin,M J
AU  - Rosen,D M
AU  - Wolff,J H
AU  - Callery,P S
AU  - Musser,S M
AU  - Eiseman,J L
TI  - Metabolism of 17-(allylamino)-17-demethoxygeldanamycin (NSC 330507) by murine and human hepatic preparations
SN  - 0008-5472
PY  - 1998///0707
KW  - Animals
KW  - Antibiotics, Antineoplastic
KW  - metabolism
KW  - Benzoquinones
KW  - Cells, Cultured
KW  - Chromatography, High Pressure Liquid
KW  - Cytochrome P-450 CYP3A
KW  - Cytochrome P-450 Enzyme System
KW  - Cytosol
KW  - drug effects
KW  - Epoxide Hydrolases
KW  - Gas Chromatography-Mass Spectrometry
KW  - Humans
KW  - Ketoconazole
KW  - pharmacology
KW  - Lactams, Macrocyclic
KW  - Liver
KW  - Mice
KW  - Microsomes, Liver
KW  - Mixed Function Oxygenases
KW  - Molecular Weight
KW  - NAD
KW  - Quinones
KW  - Rifabutin
KW  - analogs & derivatives
KW  - Species Specificity
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
ER  -