TY  - GEN
AU  - Lasker,J M
AU  - Wester,M R
AU  - Aramsombatdee,E
AU  - Raucy,J L
TI  - Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations
SN  - 0003-9861
PY  - 1998///0608
KW  - Anti-Inflammatory Agents, Non-Steroidal
KW  - metabolism
KW  - Aryl Hydrocarbon Hydroxylases
KW  - Chromatography, DEAE-Cellulose
KW  - Chromatography, Ion Exchange
KW  - Cytochrome P-450 CYP2C19
KW  - Cytochrome P-450 CYP2C8
KW  - Cytochrome P-450 CYP2C9
KW  - Cytochrome P-450 Enzyme System
KW  - isolation & purification
KW  - Electrophoresis, Polyacrylamide Gel
KW  - Humans
KW  - Hydroxylation
KW  - Kinetics
KW  - Mephenytoin
KW  - pharmacokinetics
KW  - Microsomes, Liver
KW  - enzymology
KW  - Mixed Function Oxygenases
KW  - Omeprazole
KW  - Steroid 16-alpha-Hydroxylase
KW  - Steroid Hydroxylases
KW  - Substrate Specificity
KW  - Tolbutamide
KW  - Ultrafiltration
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1006/abbi.1998.0615
ER  -