TY - GEN AU - Fersht,A R TI - Sieves in sequence SN - 0036-8075 PY - 1998///0507 KW - Adenosine Triphosphate KW - metabolism KW - Binding Sites KW - Escherichia coli KW - enzymology KW - Hydrolysis KW - Isoleucine KW - chemistry KW - Isoleucine-tRNA Ligase KW - Substrate Specificity KW - Thermus thermophilus KW - Transfer RNA Aminoacylation KW - Valine N1 - Publication Type: Journal Article; Comment UR - https://doi.org/10.1126/science.280.5363.541 ER -