TY - GEN AU - Guidez,F AU - Ivins,S AU - Zhu,J AU - Söderström,M AU - Waxman,S AU - Zelent,A TI - Reduced retinoic acid-sensitivities of nuclear receptor corepressor binding to PML- and PLZF-RARalpha underlie molecular pathogenesis and treatment of acute promyelocytic leukemia SN - 0006-4971 PY - 1998///0512 KW - Chromosomes, Human, Pair 15 KW - Chromosomes, Human, Pair 17 KW - DNA-Binding Proteins KW - genetics KW - Drug Resistance, Neoplasm KW - Gene Expression Regulation, Neoplastic KW - drug effects KW - Humans KW - Kruppel-Like Transcription Factors KW - Leukemia, Promyelocytic, Acute KW - drug therapy KW - Neoplasm Proteins KW - Nuclear Proteins KW - Nuclear Receptor Co-Repressor 1 KW - Oncogene Proteins, Fusion KW - Promyelocytic Leukemia Zinc Finger Protein KW - Protein Binding KW - Repressor Proteins KW - Transcription Factors KW - Translocation, Genetic KW - Tretinoin KW - pharmacology KW - Tumor Cells, Cultured KW - Zinc Fingers N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S ER -