Mutations in either nucleotide-binding site of P-glycoprotein (Mdr3) prevent vanadate trapping of nucleotide at both sites. [electronic resource]
- Biochemistry Mar 1998
- 4592-602 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0006-2960
10.1021/bi9728001 doi
ATP Binding Cassette Transporter, Subfamily B ATP Binding Cassette Transporter, Subfamily B, Member 1--biosynthesis ATP-Binding Cassette Transporters--biosynthesis Adenosine Triphosphatases--metabolism Adenosine Triphosphate--analogs & derivatives Affinity Labels--metabolism Azides--metabolism Base Sequence Binding Sites Enzyme Inhibitors--pharmacology Escherichia coli--metabolism Hydrolysis Lipid Metabolism Mutagenesis, Site-Directed Nucleotides--metabolism Pichia--metabolism Point Mutation Vanadates--pharmacology