Barlocco, D <br/><br/>
Mono- and disubstituted-3,8-diazabicyclo[3.2.1]octane derivatives as analgesics structurally related to epibatidine: synthesis, activity, and modeling.  [electronic resource] 

 -  Journal of medicinal chemistry  Feb 1998 
 - 674-81 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm970427p  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Abdominal Muscles--physiology<br/>Analgesia<br/>Analgesics, Non-Narcotic--chemical synthesis<br/>Animals<br/>Bridged Bicyclo Compounds, Heterocyclic--chemical synthesis<br/>Cerebral Cortex--metabolism<br/>Humans<br/>Kinetics<br/>Magnetic Resonance Spectroscopy<br/>Male<br/>Mecamylamine--pharmacology<br/>Mice<br/>Models, Molecular<br/>Molecular Conformation<br/>Muscle Contraction--drug effects<br/>Naloxone--pharmacology<br/>Narcotic Antagonists--pharmacology<br/>Pain Threshold--drug effects<br/>Pyridazines--chemical synthesis<br/>Pyridines--chemistry<br/>Rats<br/>Receptors, Cholinergic--drug effects