Bergstrom, J D
Hepatic responses to inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase: a comparison of atorvastatin and simvastatin. [electronic resource]
- Biochimica et biophysica acta Jan 1998
- 213-21 p. digital
Publication Type: Comparative Study; Journal Article
ISSN: 0006-3002
Standard No.: 10.1016/s0005-2760(97)00182-3 doi
Subjects--Topical Terms: Animals Anticholesteremic Agents--pharmacology Atorvastatin Carcinoma, Hepatocellular Cholesterol--biosynthesis Enzyme Induction Heptanoic Acids--pharmacology Humans Hydroxymethylglutaryl CoA Reductases--biosynthesis Hydroxymethylglutaryl-CoA Reductase Inhibitors--pharmacology Kinetics Liver--drug effects Liver Neoplasms Male Pyrroles--pharmacology RNA, Messenger--biosynthesis Rats Rats, Sprague-Dawley Simvastatin--pharmacology Transcription, Genetic--drug effects Tumor Cells, Cultured