TY - GEN AU - Reed,W AU - Vichinsky,E P TI - New considerations in the treatment of sickle cell disease SN - 0066-4219 PY - 1998///0430 KW - Adult KW - Africa KW - Anemia, Sickle Cell KW - complications KW - Antisickling Agents KW - therapeutic use KW - Biochemical Phenomena KW - Biochemistry KW - Blood Transfusion KW - Cause of Death KW - Chronic Disease KW - Cohort Studies KW - Cytokines KW - Ethnicity KW - Hematopoietic Stem Cell Transplantation KW - Hemoglobin, Sickle KW - genetics KW - Humans KW - Life Expectancy KW - Malaria KW - Molecular Biology KW - Mutation KW - Pain KW - physiopathology KW - Patient Care KW - Population Dynamics KW - Prevalence KW - Prospective Studies KW - Survival Rate N1 - Publication Type: Journal Article; Review UR - https://doi.org/10.1146/annurev.med.49.1.461 ER -