TY - GEN AU - Kliewer,S A AU - Moore,J T AU - Wade,L AU - Staudinger,J L AU - Watson,M A AU - Jones,S A AU - McKee,D D AU - Oliver,B B AU - Willson,T M AU - Zetterström,R H AU - Perlmann,T AU - Lehmann,J M TI - An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway SN - 0092-8674 PY - 1998///0316 KW - Amino Acid Sequence KW - Animals KW - Aryl Hydrocarbon Hydroxylases KW - Base Sequence KW - Cloning, Molecular KW - Conserved Sequence KW - genetics KW - Cytochrome P-450 CYP3A KW - Cytochrome P-450 Enzyme System KW - Embryo, Mammalian KW - chemistry KW - Gene Expression KW - Genes KW - Glucocorticoids KW - chemical synthesis KW - Histone Acetyltransferases KW - Mice KW - Molecular Sequence Data KW - Nuclear Receptor Coactivator 1 KW - Oxidoreductases, N-Demethylating KW - Pregnane X Receptor KW - Pregnanes KW - Promoter Regions, Genetic KW - Protein Binding KW - Receptors, Cytoplasmic and Nuclear KW - drug effects KW - Receptors, Steroid KW - Signal Transduction KW - Steroids KW - physiology KW - Transcription Factors KW - metabolism N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/s0092-8674(00)80900-9 ER -