TY  - GEN
AU  - Hopper,A T
AU  - Witiak,D T
AU  - Ziemniak,J
TI  - Design, synthesis, and biological evaluation of conformationally constrained aci-reductone mimics of arachidonic acid
SN  - 0022-2623
PY  - 1998///0317
KW  - Animals
KW  - Antioxidants
KW  - chemical synthesis
KW  - Arachidonate 5-Lipoxygenase
KW  - metabolism
KW  - Arachidonic Acid
KW  - chemistry
KW  - Cell Line, Transformed
KW  - Cell Nucleus
KW  - Cyclooxygenase 1
KW  - Cyclooxygenase 2
KW  - Cyclooxygenase 2 Inhibitors
KW  - Cyclooxygenase Inhibitors
KW  - Drug Design
KW  - Indicators and Reagents
KW  - Isoenzymes
KW  - Lipopolysaccharides
KW  - pharmacology
KW  - Lipoxygenase Inhibitors
KW  - Macrophages, Peritoneal
KW  - drug effects
KW  - Malondialdehyde
KW  - Membrane Proteins
KW  - Models, Molecular
KW  - Molecular Conformation
KW  - Molecular Structure
KW  - NF-kappa B
KW  - Prostaglandin-Endoperoxide Synthases
KW  - Rats
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm970034q
ER  -