Hopper, A T
Design, synthesis, and biological evaluation of conformationally constrained aci-reductone mimics of arachidonic acid. [electronic resource]
- Journal of medicinal chemistry Feb 1998
- 420-7 p. digital
Publication Type: Journal Article
ISSN: 0022-2623
Standard No.: 10.1021/jm970034q doi
Subjects--Topical Terms: Animals Antioxidants--chemical synthesis Arachidonate 5-Lipoxygenase--metabolism Arachidonic Acid--chemistry Cell Line, Transformed Cell Nucleus--metabolism Cyclooxygenase 1 Cyclooxygenase 2 Cyclooxygenase 2 Inhibitors Cyclooxygenase Inhibitors--chemical synthesis Drug Design Indicators and Reagents Isoenzymes--metabolism Lipopolysaccharides--pharmacology Lipoxygenase Inhibitors--chemical synthesis Macrophages, Peritoneal--drug effects Malondialdehyde Membrane Proteins Models, Molecular Molecular Conformation Molecular Structure NF-kappa B--metabolism Prostaglandin-Endoperoxide Synthases--metabolism Rats Structure-Activity Relationship