TY - GEN AU - Pawelek,P D AU - MacKenzie,R E TI - Methenyltetrahydrofolate cyclohydrolase is rate limiting for the enzymatic conversion of 10-formyltetrahydrofolate to 5,10-methylenetetrahydrofolate in bifunctional dehydrogenase-cyclohydrolase enzymes SN - 0006-2960 PY - 1998///0306 KW - Adenosine Diphosphate KW - pharmacology KW - Aminohydrolases KW - drug effects KW - Bacterial Proteins KW - metabolism KW - Formate-Tetrahydrofolate Ligase KW - Humans KW - Kinetics KW - Leucovorin KW - analogs & derivatives KW - Methylenetetrahydrofolate Dehydrogenase (NADP) KW - Mitochondria KW - enzymology KW - Models, Chemical KW - Multienzyme Complexes KW - NAD KW - NADP KW - Photobacterium KW - Tetrahydrofolates N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/bi971906t ER -