TY - GEN AU - Chang,Y C AU - Lee,Y S AU - Tejima,T AU - Tanaka,K AU - Omura,S AU - Heintz,N H AU - Mitsui,Y AU - Magae,J TI - mdm2 and bax, downstream mediators of the p53 response, are degraded by the ubiquitin-proteasome pathway SN - 1044-9523 PY - 1998///0206 KW - Animals KW - Cell Division KW - drug effects KW - Cell Line KW - Cysteine Endopeptidases KW - metabolism KW - Cysteine Proteinase Inhibitors KW - pharmacology KW - Humans KW - Hydrolysis KW - Leupeptins KW - Multienzyme Complexes KW - Nuclear Proteins KW - Proteasome Endopeptidase Complex KW - Proto-Oncogene Proteins KW - genetics KW - Proto-Oncogene Proteins c-bcl-2 KW - Proto-Oncogene Proteins c-mdm2 KW - Tumor Suppressor Protein p53 KW - Ubiquitins KW - bcl-2-Associated X Protein N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't ER -