Guanine-nucleotide exchange protein C3G activates JNK1 by a ras-independent mechanism. JNK1 activation inhibited by kinase negative forms of MLK3 and DLK mixed lineage kinases. [electronic resource]
- The Journal of biological chemistry Jan 1998
- 1281-4 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0021-9258
10.1074/jbc.273.3.1281 doi
Animals Calcium-Calmodulin-Dependent Protein Kinases--metabolism Cell Line Enzyme Activation Eukaryotic Initiation Factor-2--metabolism Guanine Nucleotide Exchange Factors JNK Mitogen-Activated Protein Kinases MAP Kinase Kinase 1 MAP Kinase Kinase Kinases Mitogen-Activated Protein Kinase 3 Mitogen-Activated Protein Kinase Kinases Mitogen-Activated Protein Kinases Protein Serine-Threonine Kinases--metabolism Protein-Tyrosine Kinases--metabolism Proteins--metabolism Signal Transduction ras Guanine Nucleotide Exchange Factors ras Proteins--metabolism Mitogen-Activated Protein Kinase Kinase Kinase 11