L-arginine decreases alveolar macrophage proinflammatory monokine production during acute lung injury by a nitric oxide synthase-dependent mechanism. [electronic resource]
- The Journal of trauma Dec 1997
- 888-93 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0022-5282
10.1097/00005373-199712000-00003 doi
Analysis of Variance Animals Arginine--pharmacology Bronchoalveolar Lavage Fluid--cytology Drug Evaluation, Preclinical Endotoxins--adverse effects Enzyme Inhibitors--pharmacology Interleukin-1--biosynthesis Macrophages, Alveolar--immunology Male Nitric Oxide--immunology Nitric Oxide Synthase--antagonists & inhibitors Premedication Rats Rats, Sprague-Dawley Respiratory Distress Syndrome--enzymology Time Factors Tumor Necrosis Factor-alpha--biosynthesis omega-N-Methylarginine--pharmacology