Barrington, R E

A farnesyltransferase inhibitor induces tumor regression in transgenic mice harboring multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis. [electronic resource] - Molecular and cellular biology Jan 1998 - 85-92 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0270-7306

10.1128/MCB.18.1.85 doi


Alkyl and Aryl Transferases--antagonists & inhibitors
Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Carcinoma--drug therapy
Cell Cycle--drug effects
Enzyme Inhibitors--pharmacology
Farnesyltranstransferase
Female
Genes, ras
Humans
Mammary Neoplasms, Experimental--drug therapy
Mammary Tumor Virus, Mouse
Methionine--analogs & derivatives
Mice
Mice, Transgenic
Salivary Gland Neoplasms--drug therapy