TY - GEN AU - Petit,A M AU - Rak,J AU - Hung,M C AU - Rockwell,P AU - Goldstein,N AU - Fendly,B AU - Kerbel,R S TI - Neutralizing antibodies against epidermal growth factor and ErbB-2/neu receptor tyrosine kinases down-regulate vascular endothelial growth factor production by tumor cells in vitro and in vivo: angiogenic implications for signal transduction therapy of solid tumors SN - 0002-9440 PY - 1998///0102 KW - Adenocarcinoma KW - drug therapy KW - Animals KW - Antibodies, Monoclonal KW - pharmacology KW - Breast Neoplasms KW - Carcinoma, Squamous Cell KW - Dose-Response Relationship, Drug KW - Down-Regulation KW - drug effects KW - Endothelial Growth Factors KW - metabolism KW - Epidermal Growth Factor KW - immunology KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Immunoenzyme Techniques KW - Lymphokines KW - Mice KW - Mice, Nude KW - Neoplasm Transplantation KW - Neovascularization, Pathologic KW - Neutralization Tests KW - Receptor, ErbB-2 KW - Signal Transduction KW - physiology KW - Tumor Cells, Cultured KW - Vascular Endothelial Growth Factor A KW - Vascular Endothelial Growth Factors N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S ER -