TY  - GEN
AU  - Feng,D M
AU  - Gardell,S J
AU  - Lewis,S D
AU  - Bock,M G
AU  - Chen,Z
AU  - Freidinger,R M
AU  - Naylor-Olsen,A M
AU  - Ramjit,H G
AU  - Woltmann,R
AU  - Baskin,E P
AU  - Lynch,J J
AU  - Lucas,R
AU  - Shafer,J A
AU  - Dancheck,K B
AU  - Chen,I W
AU  - Mao,S S
AU  - Krueger,J A
AU  - Hare,T R
AU  - Mulichak,A M
AU  - Vacca,J P
TI  - Discovery of a novel, selective, and orally bioavailable class of thrombin inhibitors incorporating aminopyridyl moieties at the P1 position
SN  - 0022-2623
PY  - 1997///1215
KW  - Administration, Oral
KW  - Animals
KW  - Antithrombins
KW  - chemical synthesis
KW  - Biological Availability
KW  - Crystallography, X-Ray
KW  - Dipeptides
KW  - Dogs
KW  - Kinetics
KW  - Pyridines
KW  - Rats
KW  - Structure-Activity Relationship
KW  - Thrombin
KW  - antagonists & inhibitors
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm970493r
ER  -