TY - GEN AU - Sall,D J AU - Bastian,J A AU - Briggs,S L AU - Buben,J A AU - Chirgadze,N Y AU - Clawson,D K AU - Denney,M L AU - Giera,D D AU - Gifford-Moore,D S AU - Harper,R W AU - Hauser,K L AU - Klimkowski,V J AU - Kohn,T J AU - Lin,H S AU - McCowan,J R AU - Palkowitz,A D AU - Smith,G F AU - Takeuchi,K AU - Thrasher,K J AU - Tinsley,J M AU - Utterback,B G AU - Yan,S C AU - Zhang,M TI - Dibasic benzo[b]thiophene derivatives as a novel class of active site-directed thrombin inhibitors. 1. Determination of the serine protease selectivity, structure-activity relationships, and binding orientation SN - 0022-2623 PY - 1997///1211 KW - Animals KW - Binding Sites KW - Crystallography, X-Ray KW - Humans KW - Serine Proteinase Inhibitors KW - chemistry KW - Structure-Activity Relationship KW - Thiophenes KW - Thrombin KW - antagonists & inhibitors N1 - Publication Type: Journal Article UR - https://doi.org/10.1021/jm9704107 ER -