Terpstra, W

Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor eliminates acute myeloid leukemia cells with the potential to initiate leukemia in immunodeficient mice, but spares normal hemopoietic stem cells. [electronic resource] - Blood Nov 1997 - 3735-42 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-4971


Acute Disease
Animals
Cell Death--drug effects
Diphtheria Toxin--genetics
Granulocyte-Macrophage Colony-Stimulating Factor--genetics
Hematopoietic Stem Cells--drug effects
Humans
Leukemia, Experimental--drug therapy
Leukemia, Myeloid--drug therapy
Mice
Mice, SCID
Neoplasm Transplantation
Recombinant Fusion Proteins--genetics