Odani, A

Genetic polymorphism of the CYP2C subfamily and its effect on the pharmacokinetics of phenytoin in Japanese patients with epilepsy. [electronic resource] - Clinical pharmacology and therapeutics Sep 1997 - 287-92 p. digital

Publication Type: Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0009-9236

10.1016/S0009-9236(97)90031-X doi


Adolescent
Adult
Anticonvulsants--pharmacokinetics
Aryl Hydrocarbon Hydroxylases
Bayes Theorem
Child
Child, Preschool
Cytochrome P-450 CYP2C19
Cytochrome P-450 CYP2C9
Cytochrome P-450 Enzyme System--chemistry
Epilepsy--drug therapy
Female
Gene Expression Regulation, Enzymologic--genetics
Genotype
Heterozygote
Humans
Infant
Japan
Male
Mixed Function Oxygenases--chemistry
Mutation--genetics
Phenytoin--blood
Polymerase Chain Reaction
Polymorphism, Genetic
Steroid 16-alpha-Hydroxylase
Steroid Hydroxylases--chemistry