Odani, A
Genetic polymorphism of the CYP2C subfamily and its effect on the pharmacokinetics of phenytoin in Japanese patients with epilepsy. [electronic resource]
- Clinical pharmacology and therapeutics Sep 1997
- 287-92 p. digital
Publication Type: Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
ISSN: 0009-9236
Standard No.: 10.1016/S0009-9236(97)90031-X doi
Subjects--Topical Terms: Adolescent Adult Anticonvulsants--pharmacokinetics Aryl Hydrocarbon Hydroxylases Bayes Theorem Child Child, Preschool Cytochrome P-450 CYP2C19 Cytochrome P-450 CYP2C9 Cytochrome P-450 Enzyme System--chemistry Epilepsy--drug therapy Female Gene Expression Regulation, Enzymologic--genetics Genotype Heterozygote Humans Infant Japan Male Mixed Function Oxygenases--chemistry Mutation--genetics Phenytoin--blood Polymerase Chain Reaction Polymorphism, Genetic Steroid 16-alpha-Hydroxylase Steroid Hydroxylases--chemistry