TY  - GEN
AU  - Ren,S
AU  - Yang,J S
AU  - Kalhorn,T F
AU  - Slattery,J T
TI  - Oxidation of cyclophosphamide to 4-hydroxycyclophosphamide and deschloroethylcyclophosphamide in human liver microsomes
SN  - 0008-5472
PY  - 1997///1028
KW  - Aryl Hydrocarbon Hydroxylases
KW  - Biotransformation
KW  - Cyclophosphamide
KW  - analogs & derivatives
KW  - Cytochrome P-450 CYP2C9
KW  - Cytochrome P-450 CYP3A
KW  - Cytochrome P-450 Enzyme Inhibitors
KW  - Cytochrome P-450 Enzyme System
KW  - genetics
KW  - Enzyme Inhibitors
KW  - pharmacology
KW  - Humans
KW  - Isoenzymes
KW  - antagonists & inhibitors
KW  - Kinetics
KW  - Microsomes, Liver
KW  - metabolism
KW  - Mixed Function Oxygenases
KW  - Orphenadrine
KW  - Oxidation-Reduction
KW  - Prodrugs
KW  - Recombinant Fusion Proteins
KW  - Steroid 16-alpha-Hydroxylase
KW  - Steroid Hydroxylases
KW  - Troleandomycin
N1  - Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S
ER  -