Hypericin-induced apoptosis of human malignant glioma cells is light-dependent, independent of bcl-2 expression, and does not require wild-type p53. [electronic resource]
- Neurological research Oct 1997
- 459-70 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0161-6412
Anthracenes Antibiotics, Antineoplastic--pharmacology Antineoplastic Agents--pharmacology Antineoplastic Agents, Hormonal--pharmacology Apoptosis--physiology Cell Division--drug effects Drug Resistance Glioma--pathology Humans Light Naphthalenes--pharmacology Perylene--analogs & derivatives Protein Kinase C--antagonists & inhibitors Protein Synthesis Inhibitors--pharmacology Proto-Oncogene Proteins--metabolism Proto-Oncogene Proteins c-bcl-2--metabolism RNA--antagonists & inhibitors Tamoxifen--pharmacology Tumor Cells, Cultured--drug effects Tumor Suppressor Protein p53--physiology bcl-2-Associated X Protein fas Receptor--physiology