Lau, C K <br/><br/>
From indomethacin to a selective COX-2 inhibitor. Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors.  [electronic resource] 

 -  Advances in experimental medicine and biology  1997 
 - 73-8 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article 
<br/><br/><label>ISSN: </label>0065-2598 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Anti-Inflammatory Agents, Non-Steroidal--chemical synthesis<br/>Carrageenan--toxicity<br/>Chromium Radioisotopes<br/>Cyclooxygenase 1<br/>Cyclooxygenase 2<br/>Cyclooxygenase 2 Inhibitors<br/>Cyclooxygenase Inhibitors--chemical synthesis<br/>Digestive System--drug effects<br/>Edema--chemically induced<br/>Feces--chemistry<br/>Fever--chemically induced<br/>Indomethacin--analogs & derivatives<br/>Isoenzymes--drug effects<br/>Membrane Proteins<br/>Molecular Conformation<br/>Molecular Structure<br/>Neoplasm Proteins--antagonists & inhibitors<br/>Prostaglandin-Endoperoxide Synthases--drug effects<br/>Rats<br/>Structure-Activity Relationship<br/>Substrate Specificity<br/>Tumor Cells, Cultured