TY - GEN AU - Ren,S AU - Lawson,A E AU - Carr,M AU - Baumgarten,C M AU - Schwartz,L B TI - Human tryptase fibrinogenolysis is optimal at acidic pH and generates anticoagulant fragments in the presence of the anti-tryptase monoclonal antibody B12 SN - 0022-1767 PY - 1997///1021 KW - Adjuvants, Immunologic KW - pharmacology KW - Antibodies, Monoclonal KW - metabolism KW - Binding, Competitive KW - immunology KW - Catalysis KW - Chymases KW - Dextran Sulfate KW - Drug Stability KW - Fibrinogen KW - Fibrinolysin KW - Fibrinolysis KW - Humans KW - Hydrogen-Ion Concentration KW - Hypersensitivity, Immediate KW - Male KW - Middle Aged KW - Oligopeptides KW - Peptide Fragments KW - Serine Endopeptidases KW - Serine Proteinase Inhibitors KW - Skin Tests KW - Substrate Specificity KW - Tryptases N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S ER -