TY - GEN AU - Nestler,E J AU - Aghajanian,G K TI - Molecular and cellular basis of addiction SN - 0036-8075 PY - 1997///1023 KW - Adaptation, Physiological KW - Animals KW - Brain KW - drug effects KW - Cyclic AMP KW - metabolism KW - Down-Regulation KW - GTP-Binding Proteins KW - Humans KW - Illicit Drugs KW - pharmacology KW - Receptors, Neurotransmitter KW - Substance-Related Disorders KW - Synaptic Transmission KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review UR - https://doi.org/10.1126/science.278.5335.58 ER -