MacFadyen, R J <br/><br/>
Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients.  [electronic resource] 

 -  Cardiovascular research  Jul 1997 
 - 30-4 p.  digital 
<br/><br/> Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial 
<br/><br/><label>ISSN: </label>0008-6363 
<br/><br/><label>Standard No.: </label>10.1016/s0008-6363(97)00091-6  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aged<br/>Angiotensin-Converting Enzyme Inhibitors--therapeutic use<br/>Biomarkers--blood<br/>Circadian Rhythm<br/>Diuretics--therapeutic use<br/>Double-Blind Method<br/>Drug Therapy, Combination<br/>Electrocardiography, Ambulatory<br/>Female<br/>Fibrosis<br/>Heart Failure--blood<br/>Heart Rate--drug effects<br/>Humans<br/>Male<br/>Mineralocorticoid Receptor Antagonists--therapeutic use<br/>Myocardium--pathology<br/>Peptide Fragments--blood<br/>Procollagen--blood<br/>Spironolactone--therapeutic use