Comparison of 6-s-cis- and 6-s-trans-locked analogs of 1alpha,25-dihydroxyvitamin D3 indicates that the 6-s-cis conformation is preferred for rapid nongenomic biological responses and that neither 6-s-cis- nor 6-s-trans-locked analogs are preferred for genomic biological responses. [electronic resource]
- Molecular endocrinology (Baltimore, Md.) Sep 1997
- 1518-31 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0888-8809
10.1210/mend.11.10.9993 doi
Animals COS Cells Calcitriol--analogs & derivatives Genome HL-60 Cells Humans Protein Conformation Signal Transduction--genetics