Interaction of CTLA-4 with the clathrin-associated protein AP50 results in ligand-independent endocytosis that limits cell surface expression. [electronic resource]
- Journal of immunology (Baltimore, Md. : 1950) Jul 1997
- 144-51 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0022-1767
Abatacept Adaptor Protein Complex 2 Adaptor Protein Complex mu Subunits Adaptor Proteins, Vesicular Transport Amino Acid Sequence Antigens, CD Antigens, Differentiation--genetics CTLA-4 Antigen Endocytosis--immunology Humans Immunoconjugates Jurkat Cells Lymphocyte Activation--immunology Molecular Sequence Data Mutation Nerve Tissue Proteins--immunology Phosphoproteins--immunology Receptor Aggregation Signal Transduction--immunology T-Lymphocytes--immunology