TY - GEN AU - Stanulla,M AU - Wang,J AU - Chervinsky,D S AU - Thandla,S AU - Aplan,P D TI - DNA cleavage within the MLL breakpoint cluster region is a specific event which occurs as part of higher-order chromatin fragmentation during the initial stages of apoptosis SN - 0270-7306 PY - 1997///0724 KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - Core Binding Factor Alpha 2 Subunit KW - DNA Fragmentation KW - drug effects KW - DNA-Binding Proteins KW - genetics KW - Enzyme Inhibitors KW - adverse effects KW - Etoposide KW - Histone-Lysine N-Methyltransferase KW - Humans KW - Mice KW - Myeloid-Lymphoid Leukemia Protein KW - Proto-Oncogene Proteins KW - Proto-Oncogenes KW - Restriction Mapping KW - Species Specificity KW - Topoisomerase II Inhibitors KW - Transcription Factors KW - Translocation, Genetic KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1128/MCB.17.7.4070 ER -