Akama, T Design and synthesis of potent antitumor 5,4'-diaminoflavone derivatives based on metabolic considerations. [electronic resource] - Journal of medicinal chemistry Jun 1997 - 1894-900 p. digital Publication Type: Journal Article ISSN: 0022-2623 Standard No.: 10.1021/jm9700326 doi Subjects--Topical Terms: AnimalsAntineoplastic Agents--chemical synthesisBreast Neoplasms--chemistryCell Division--drug effectsDrug DesignEndometrial Neoplasms--pathologyFemaleFlavonoids--chemical synthesisHumansLiver Neoplasms--pathologyMiceMice, Inbred BALB CMice, NudeMolecular StructureNeoplasm TransplantationNeoplasms, Experimental--drug therapyOvarian Neoplasms--pathologyReceptors, Estradiol--analysisStructure-Activity RelationshipTumor Cells, Cultured