TY  - GEN
AU  - Edwards,P D
AU  - Andisik,D W
AU  - Bryant,C A
AU  - Ewing,B
AU  - Gomes,B
AU  - Lewis,J J
AU  - Rakiewicz,D
AU  - Steelman,G
AU  - Strimpler,A
AU  - Trainor,D A
AU  - Tuthill,P A
AU  - Mauger,R C
AU  - Veale,C A
AU  - Wildonger,R A
AU  - Williams,J C
AU  - Wolanin,D J
AU  - Zottola,M
TI  - Discovery and biological activity of orally active peptidyl trifluoromethyl ketone inhibitors of human neutrophil elastase
SN  - 0022-2623
PY  - 1997///0715
KW  - Administration, Oral
KW  - Animals
KW  - Body Weight
KW  - drug effects
KW  - Cricetinae
KW  - Dipeptides
KW  - chemical synthesis
KW  - Enzyme Inhibitors
KW  - administration & dosage
KW  - Erythrocyte Count
KW  - Hemorrhage
KW  - prevention & control
KW  - Humans
KW  - Leukocyte Count
KW  - Leukocyte Elastase
KW  - antagonists & inhibitors
KW  - Lung
KW  - anatomy & histology
KW  - Lung Diseases
KW  - Male
KW  - Mesocricetus
KW  - Molecular Structure
KW  - Organ Size
KW  - Structure-Activity Relationship
KW  - Trachea
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm960819g
ER  -