TY  - GEN
AU  - Rep,M H
AU  - van Oosten,B W
AU  - Roos,M T
AU  - Adèr,H J
AU  - Polman,C H
AU  - van Lier,R A
TI  - Treatment with depleting CD4 monoclonal antibody results in a preferential loss of circulating naive T cells but does not affect IFN-gamma secreting TH1 cells in humans
SN  - 0021-9738
PY  - 1997///0624
KW  - Adult
KW  - Antibodies, Monoclonal
KW  - therapeutic use
KW  - CD4 Antigens
KW  - immunology
KW  - CD4-Positive T-Lymphocytes
KW  - CD8-Positive T-Lymphocytes
KW  - Double-Blind Method
KW  - Female
KW  - Humans
KW  - Interferon-gamma
KW  - biosynthesis
KW  - Interleukin-4
KW  - Leukocyte Common Antigens
KW  - Lymphocyte Depletion
KW  - Male
KW  - Middle Aged
KW  - Multiple Sclerosis
KW  - T-Lymphocyte Subsets
KW  - Th1 Cells
KW  - Th2 Cells
KW  - fas Receptor
N1  - Publication Type: Clinical Trial; Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1172/JCI119396
ER  -