TY - GEN AU - Guo,Q AU - Sopher,B L AU - Furukawa,K AU - Pham,D G AU - Robinson,N AU - Martin,G M AU - Mattson,M P TI - Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals SN - 0270-6474 PY - 1997///0610 KW - Alzheimer Disease KW - genetics KW - Amyloid beta-Peptides KW - pharmacology KW - Animals KW - Antioxidants KW - Apoptosis KW - drug effects KW - Blood Proteins KW - Calcium KW - metabolism KW - Dantrolene KW - Endoplasmic Reticulum KW - physiology KW - Enzyme Inhibitors KW - Fura-2 KW - Homeostasis KW - Humans KW - Membrane Proteins KW - Muscle Relaxants, Central KW - Mutation KW - Nerve Growth Factors KW - Neurons KW - Oxidative Stress KW - PC12 Cells KW - cytology KW - Presenilin-1 KW - Proto-Oncogene Proteins c-bcl-2 KW - Rats KW - Reactive Oxygen Species KW - Thapsigargin KW - Transfection N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S ER -