Guo, Q

Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Jun 1997 - 4212-22 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0270-6474


Alzheimer Disease--genetics
Amyloid beta-Peptides--pharmacology
Animals
Antioxidants--pharmacology
Apoptosis--drug effects
Blood Proteins--pharmacology
Calcium--metabolism
Dantrolene--pharmacology
Endoplasmic Reticulum--physiology
Enzyme Inhibitors--pharmacology
Fura-2
Homeostasis--physiology
Humans
Membrane Proteins--genetics
Muscle Relaxants, Central--pharmacology
Mutation--physiology
Nerve Growth Factors--pharmacology
Neurons--drug effects
Oxidative Stress--physiology
PC12 Cells--cytology
Presenilin-1
Proto-Oncogene Proteins c-bcl-2--physiology
Rats
Reactive Oxygen Species--metabolism
Thapsigargin--pharmacology
Transfection