Bromocriptine transcriptionally activates the multidrug resistance gene (pgp2/mdr1b) by a novel pathway. [electronic resource]
- The Journal of biological chemistry Apr 1997
- 11518-25 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0021-9258
10.1074/jbc.272.17.11518 doi
ATP Binding Cassette Transporter, Subfamily B, Member 1--biosynthesis Amino Acid Sequence Animals Bromocriptine--pharmacology Dopamine Agonists--pharmacology Dopamine Antagonists--pharmacology Dose-Response Relationship, Drug Drug Resistance, Multiple--genetics GTP-Binding Proteins--metabolism Genes, MDR Molecular Sequence Data Protein Serine-Threonine Kinases--metabolism Proto-Oncogene Proteins--metabolism Proto-Oncogene Proteins c-raf Rats Receptors, Dopamine D1--metabolism Receptors, Dopamine D2--metabolism Signal Transduction Transcription, Genetic Tumor Cells, Cultured Up-Regulation