TY - GEN AU - Thornton,B P AU - Vetvicka,V AU - Ross,G D TI - Function of C3 in a humoral response: iC3b/C3dg bound to an immune complex generated with natural antibody and a primary antigen promotes antigen uptake and the expression of co-stimulatory molecules by all B cells, but only stimulates immunoglobulin synthesis by antigen-specific B cells SN - 0009-9104 PY - 1997///0505 KW - Antibodies, Monoclonal KW - immunology KW - Antibody Formation KW - Antibody Specificity KW - Antigen Presentation KW - Antigen-Antibody Complex KW - B-Lymphocytes KW - Cells, Cultured KW - Complement C3b KW - Complement C3d KW - Enzyme-Linked Immunosorbent Assay KW - Hemocyanins KW - Humans KW - Immunoglobulin G KW - Immunoglobulin M KW - Leukocytes, Mononuclear KW - Lymphocyte Activation KW - Lymphocyte Function-Associated Antigen-1 KW - Receptors, Complement 3d KW - Receptors, IgG N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1046/j.1365-2249.1996.57761.x ER -