TY - GEN AU - Dean,A M AU - Golding,G B TI - Protein engineering reveals ancient adaptive replacements in isocitrate dehydrogenase SN - 0027-8424 PY - 1997///0508 KW - Amino Acid Sequence KW - Isocitrate Dehydrogenase KW - genetics KW - Molecular Sequence Data KW - NADP KW - metabolism KW - Phylogeny KW - Protein Engineering KW - Sequence Homology, Amino Acid KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1073/pnas.94.7.3104 ER -