TY - GEN AU - Delbressine,L P AU - Vos,R M TI - The clinical relevance of preclinical data: mirtazapine, a model compound SN - 0271-0749 PY - 1997///0619 KW - Animals KW - Antidepressive Agents, Tricyclic KW - metabolism KW - Area Under Curve KW - Biological Availability KW - Biotransformation KW - Brain KW - Cytochrome P-450 Enzyme Inhibitors KW - Cytochrome P-450 Enzyme System KW - Depressive Disorder KW - drug therapy KW - Half-Life KW - Humans KW - Liver KW - drug effects KW - Metabolic Clearance Rate KW - Mianserin KW - analogs & derivatives KW - Mirtazapine KW - Polymorphism, Genetic KW - Protein Binding N1 - Publication Type: Journal Article; Review UR - https://doi.org/10.1097/00004714-199704001-00004 ER -