Fertala, A

Collagen II containing a Cys substitution for arg-alpha1-519. Homotrimeric monomers containing the mutation do not assemble into fibrils but alter the self-assembly of the normal protein. [electronic resource] - The Journal of biological chemistry Mar 1997 - 6457-64 p. digital

Publication Type: Journal Article

0021-9258

10.1074/jbc.272.10.6457 doi


Amino Acid Sequence
Arginine
Collagen--chemistry
Computer Simulation
Cysteine
Exostoses, Multiple Hereditary--genetics
Humans
Macromolecular Substances
Microscopy, Electron
Molecular Sequence Data
Osteoarthritis--genetics
Point Mutation
Protein Binding
Protein Denaturation
Protein Structure, Tertiary
Structure-Activity Relationship