Lamb, D C <br/><br/>
The mutation T315A in Candida albicans sterol 14alpha-demethylase causes reduced enzyme activity and fluconazole resistance through reduced affinity.  [electronic resource] 

 -  The Journal of biological chemistry  Feb 1997 
 - 5682-8 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0021-9258 
<br/><br/><label>Standard No.: </label>10.1074/jbc.272.9.5682  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Sequence<br/>Animals<br/>Antifungal Agents--pharmacology<br/>Candida albicans--enzymology<br/>Cytochrome P-450 Enzyme System--genetics<br/>Drug Resistance, Microbial<br/>Electron Spin Resonance Spectroscopy<br/>Fluconazole--pharmacology<br/>Humans<br/>Kinetics<br/>Molecular Sequence Data<br/>Mutagenesis<br/>Oxidoreductases--genetics<br/>Rats<br/>Restriction Mapping<br/>Sequence Alignment<br/>Sterol 14-Demethylase