TY  - GEN
AU  - Wang,D Z
AU  - Hammond,V E
AU  - Abud,H E
AU  - Bertoncello,I
AU  - McAvoy,J W
AU  - Bowtell,D D
TI  - Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development
SN  - 0890-9369
PY  - 1997///0304
KW  - Alleles
KW  - Animals
KW  - Calcium-Calmodulin-Dependent Protein Kinases
KW  - metabolism
KW  - Embryo, Mammalian
KW  - abnormalities
KW  - Enhancer Elements, Genetic
KW  - Enzyme Activation
KW  - ErbB Receptors
KW  - genetics
KW  - Female
KW  - Fetal Death
KW  - Fibroblasts
KW  - Gene Deletion
KW  - Gene Targeting
KW  - Genes, Dominant
KW  - Guanine Nucleotide Exchange Factors
KW  - Heart Defects, Congenital
KW  - embryology
KW  - Hematopoietic Stem Cells
KW  - Heterozygote
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mutagenesis
KW  - Phenotype
KW  - Proteins
KW  - Signal Transduction
KW  - Stem Cells
KW  - ras Guanine Nucleotide Exchange Factors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1101/gad.11.3.309
ER  -