TY - GEN AU - Mendez,M J AU - Green,L L AU - Corvalan,J R AU - Jia,X C AU - Maynard-Currie,C E AU - Yang,X D AU - Gallo,M L AU - Louie,D M AU - Lee,D V AU - Erickson,K L AU - Luna,J AU - Roy,C M AU - Abderrahim,H AU - Kirschenbaum,F AU - Noguchi,M AU - Smith,D H AU - Fukushima,A AU - Hales,J F AU - Klapholz,S AU - Finer,M H AU - Davis,C G AU - Zsebo,K M AU - Jakobovits,A TI - Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice SN - 1061-4036 PY - 1997///0310 KW - Amino Acid Sequence KW - Animals KW - Antibodies, Monoclonal KW - biosynthesis KW - Antibody Affinity KW - Antibody Diversity KW - Antibody Formation KW - B-Lymphocytes KW - cytology KW - Chromosomes, Artificial, Yeast KW - genetics KW - ErbB Receptors KW - immunology KW - Gene Rearrangement, B-Lymphocyte KW - Genes, Immunoglobulin KW - Humans KW - Hybridomas KW - Immunoglobulin Heavy Chains KW - Immunoglobulin kappa-Chains KW - Interleukin-8 KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Mice, Transgenic KW - Molecular Sequence Data KW - Species Specificity KW - Transgenes KW - Tumor Necrosis Factor-alpha N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/ng0297-146 ER -