Amacher, D E
Hepatic microsomal enzyme induction, beta-oxidation, and cell proliferation following administration of clofibrate, gemfibrozil, or bezafibrate in the CD rat. [electronic resource]
- Toxicology and applied pharmacology Jan 1997
- 143-50 p. digital
Publication Type: Comparative Study; Journal Article
ISSN: 0041-008X
Standard No.: 10.1006/taap.1996.8007 doi
Subjects--Topical Terms: Animals Anticholesteremic Agents--pharmacology Bezafibrate--pharmacology Clofibrate--pharmacology Cyclin-Dependent Kinases--biosynthesis Cytochrome P-450 CYP1A1--biosynthesis Cytochrome P-450 CYP4A Cytochrome P-450 Enzyme System--biosynthesis Dose-Response Relationship, Drug Enzyme Induction--drug effects Female Gemfibrozil--pharmacology Isoenzymes--biosynthesis Liver--drug effects Male Microbodies--drug effects Microsomes, Liver--drug effects Mixed Function Oxygenases--biosynthesis Organ Size--drug effects Oxidation-Reduction Palmitoyl Coenzyme A--metabolism Proliferating Cell Nuclear Antigen--biosynthesis Rats Rats, Inbred Strains--genetics Sex Characteristics