TY - GEN AU - Vorstenbosch,E AU - Pape,T AU - Rodnina,M V AU - Kraal,B AU - Wintermeyer,W TI - The G222D mutation in elongation factor Tu inhibits the codon-induced conformational changes leading to GTPase activation on the ribosome SN - 0261-4189 PY - 1997///0127 KW - Codon KW - Enzyme Activation KW - Escherichia coli KW - metabolism KW - GTP Phosphohydrolase-Linked Elongation Factors KW - Guanosine Triphosphate KW - Guanylyl Imidodiphosphate KW - Kinetics KW - Magnesium KW - Models, Structural KW - Models, Theoretical KW - Mutagenesis, Site-Directed KW - Peptide Elongation Factor Tu KW - biosynthesis KW - Point Mutation KW - Protein Conformation KW - Protein Structure, Secondary KW - RNA, Transfer, Amino Acyl KW - RNA, Transfer, Phe KW - Recombinant Proteins KW - Ribosomes KW - Thermus N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't ER -